ELISPOT Refinement Using Spot Morphology for Assessing Host Responses to Tuberculosis

@inproceedings{Sibley2012ELISPOTRU,
  title={ELISPOT Refinement Using Spot Morphology for Assessing Host Responses to Tuberculosis},
  author={Laura S. Sibley and Andrew D. White and Alice Marriott and Michael J. Dennis and Ann Williams and Philip David Marsh and Sally A. Sharpe},
  booktitle={Cells},
  year={2012}
}
Tuberculosis is a global health problem. The Mycobacterium bovis Bacille Calmette Guerin (BCG) vaccine has variable efficacy (0-80%) so there is a drive to develop novel vaccines. The cytokine, interferon gamma (IFNγ), is an essential component of the protective response to M. tuberculosis (M. tb) infection and is also produced in response to BCG… CONTINUE READING