ELF5-Mediated AR Activation Regulates Prostate Cancer Progression

Abstract

The transcription factor E74-like factor 5 (ELF5) is a potent antioncogene that can prevent epithelial-mesenchymal transition (EMT) and metastasis in prostate cancer (PCa). However, little is known how it suppress the tumor growth and if it can interact with androgen receptor (AR). In this study, we find that the ELF5 is frequently expressed in AR activated… (More)
DOI: 10.1038/srep42759

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