ELECTRON SHADOW MICROGRAPHY OF THE TOBACCO MOSAIC VIRUS PROTEIN

@article{Williams1945ELECTRONSM,
  title={ELECTRON SHADOW MICROGRAPHY OF THE TOBACCO MOSAIC VIRUS PROTEIN},
  author={Robley Cook Williams and Ralph Walter Graystone Wyckoff},
  journal={Science},
  year={1945},
  volume={101},
  pages={594 - 596}
}
Two improvements are described in the use of shadow electron micrography for the observation of particles of macromolecular dimensions. One involves the substitution of gold for chromium as shadowing metal. The thinner gold film that can be employed gives a truer representation of the shape of particles so small that shape and size are significantly altered by the thickness of the shadowing metal deposited on them. The other consists in metal-shadowing small particles deposited on a very smooth… Expand
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  • Materials Science, Medicine
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  • K. Peters
  • Materials Science, Medicine
  • Journal of ultrastructure research
  • 1977
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In order to gain more exact information regarding the influence of pH on linear aggregation, electron microscope studies were made at two commonly used pH values, 5.6 that of tobacco leaf extract and at 7.0. Expand
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Summary A new procedure is described for the electron microscopy of small objects. This technique, illustrated by photographs of purified influenza and tobacco mosaic viruses, involves the obliqueExpand
A STUDY OF PURIFIED VIRUSES WITH THE ELECTRON MICROSCOPE
Viruses were discovered in 1892 when Iwanowski (1) observed that the agent causing the mosaic disease of tobacco passed through a filter which retained all of the bacteria then known. During theExpand