EIF3D promotes gallbladder cancer development by stabilizing GRK2 kinase and activating PI3K-AKT signaling pathway

Abstract

Recent evidence suggests that dysregulated eIF3d expression may be critical in various genetic disorders as well as cancer. In this study, we observed that EIF3d levels increased in gallbladder cancer (GBC) samples compared with non-tumor tissue. High eIF3d levels were associated with advanced tumor stage and metastasis and were correlated with poor… (More)
DOI: 10.1038/cddis.2017.263

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Cite this paper

@inproceedings{Zhang2017EIF3DPG, title={EIF3D promotes gallbladder cancer development by stabilizing GRK2 kinase and activating PI3K-AKT signaling pathway}, author={Fei Zhang and Shanshan Xiang and Yang Cao and Mao-lan Li and Qiang Ma and Haibin Liang and Huaifeng Li and Yuanyuan Ye and Yijian Zhang and Lin Jiang and Yunping Hu and Jian Zhou and Xuefeng Wang and Yong Zhang and Lei Nie and Xiao Liang and Wei Gong and Yingbin Liu}, booktitle={Cell death & disease}, year={2017} }