EHD 2 regulates caveolar dynamics via ATP-driven targeting and oligomerization

  • Björn Moréna, Claudio Shahb, +5 authors Richard Lundmarka
  • Published 2012
Eps15 homology domain–containing 2 (EHD2) belongs to the EHD-containing protein family of dynamin-related ATPases involved in membrane remodeling in the endosomal system. EHD2 dimers oligomerize into rings on highly curved membranes, resulting in stimulation of the intrinsic ATPase activity. In this paper, we report that EHD2 is specifically and stably… CONTINUE READING