EGFR signaling upregulates surface expression of the GluN2B-containing NMDA receptor and contributes to long-term potentiation in the hippocampus.

Abstract

N-methyl-d-aspartate receptors (NMDARs) have been known to be regulated by various receptor tyrosine kinases. Activation of epidermal growth factor receptor (EGFR) specifically increases NMDAR-mediated currents and enhances long-term potentiation (LTP) in the hippocampus. However, the mechanism through which EGFR regulates NMDARs remains to be elucidated… (More)
DOI: 10.1016/j.neuroscience.2015.07.021

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Cite this paper

@article{Tang2015EGFRSU, title={EGFR signaling upregulates surface expression of the GluN2B-containing NMDA receptor and contributes to long-term potentiation in the hippocampus.}, author={Y. Tang and M. Y{\'e} and Y. Du and Xiao Qiu and X. Lv and W. Yang and Jianhong Luo}, journal={Neuroscience}, year={2015}, volume={304}, pages={109-21} }