EGFR signaling pathway in breast cancers: from traditional signal transduction to direct nuclear translocalization

Abstract

Aberrant epidermal growth factor receptor (EGFR) signaling is a major characteristic of many human malignancies including breast cancer. Since the discovery of EGF in 1960’s and its receptor in 1980’s, our understanding of the EGF/EGFR pathway has been significantly advanced and consequently, EGFR is considered as a major oncogenic factor and an attractive… (More)
DOI: 10.1007/s10549-005-9011-0

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Cite this paper

@article{Lo2005EGFRSP, title={EGFR signaling pathway in breast cancers: from traditional signal transduction to direct nuclear translocalization}, author={Hui-wen Lo and Sheng-Chieh Hsu and Mien-Chie Hung}, journal={Breast Cancer Research and Treatment}, year={2005}, volume={95}, pages={211-218} }