EGFR inhibitors augment antitumour helper T-cell responses of HER family-specific immunotherapy

@inproceedings{Kumai2013EGFRIA,
  title={EGFR inhibitors augment antitumour helper T-cell responses of HER family-specific immunotherapy},
  author={Takumi Kumai and Yasuhiro Matsuda and Kensuke Oikawa and Naoya Aoki and Shun Kimura and Yasuaki Harabuchi and Esteban Celis and Hiroyuki Kobayashi},
  booktitle={British Journal of Cancer},
  year={2013}
}
Background:Head and neck squamous cell carcinoma (HNSCC) is a major cause of cancer-related morbidity and mortality worldwide. Epidermal growth factor receptor (EGFR)-targeted therapy is an attractive strategy alternative to conventional cancer treatments for HNSCC, but its efficacy remains controversial. T-cell-based immunotherapy has been proposed as a novel therapeutic approach to improve the clinical outcome for HNSCC. In this study, we report human epidermal receptor (HER) family epitopes… CONTINUE READING