EGFR-Targeted Therapeutics: Focus on SCCHN and NSCLC

  title={EGFR-Targeted Therapeutics: Focus on SCCHN and NSCLC},
  author={Martin Sattler and Oyewale Abidoye and Ravi Salgia},
Cancers of the head and neck and of the lung are associated with high morbidity and mortality rates that have remained relatively unchanged for more than 3 decades, despite advances in radiation therapies and chemotherapies over the same time. It is generally believed that the efficacy of standard therapy regimens has reached a plateau for these cancers. The discovery of specific aberrant molecular signaling pathways in solid tumors has afforded promising new directions for newer "targeted… CONTINUE READING


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