EGFR, BRAF and KRAS Status in Patients Undergoing Pulmonary Metastasectomy from Primary Colorectal Carcinoma: A Prospective Follow-Up Study

@article{Schweiger2013EGFRBA,
  title={EGFR, BRAF and KRAS Status in Patients Undergoing Pulmonary Metastasectomy from Primary Colorectal Carcinoma: A Prospective Follow-Up Study},
  author={Thomas Schweiger and Balazs Heged{\"u}s and Christoph Nikolowsky and Zita Heged{\"u}s and Ildiko Szirtes and Roland Mair and Peter Birner and Bal{\'a}zs D{\"o}me and Gyoergy Lang and Walter Klepetko and Hendrik Jan Ankersmit and Konrad Hoetzenecker},
  journal={Annals of Surgical Oncology},
  year={2013},
  volume={21},
  pages={946-954}
}
BackgroundPulmonary metastasectomy is an integral part of the interdisciplinary treatment of patients with pulmonary metastases (PMs) from colorectal carcinoma (CRC). Although alterations in the epidermal growth factor receptor (EGFR) pathway are common in CRC, there is still insufficient data regarding PM. We hypothesized that EGFR expression and Kirsten rat sarcoma viral oncogene homolog (KRAS)/BRAF mutations (Mts) might be associated with clinicopathological variables and the outcome in… CONTINUE READING

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References

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SHOWING 1-10 OF 30 REFERENCES

Long-term results after repeated surgical removal of pulmonary metastases

D Kandioler, E Kromer, H Tuchler
  • Ann Thorac Surg
  • 1998
VIEW 6 EXCERPTS
HIGHLY INFLUENTIAL

KRAS mutation is associated with lung metastasis in patients with curatively resected colorectal cancer.

  • Clinical cancer research : an official journal of the American Association for Cancer Research
  • 2011
VIEW 9 EXCERPTS
HIGHLY INFLUENTIAL

Prognostic factors in pulmonary metastasectomy: spotlight on molecular and radiological markers.

  • European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery
  • 2014
VIEW 2 EXCERPTS