EGF receptor signaling enhances in vivo invasiveness of DU-145 human prostate carcinoma cells

Abstract

Carcinomas of the prostate and other lineages often present an autocrine stimulatory loop acting via the EGF receptor (EGFR). We have recently shown that EGFR-mediated signals enhance DU-145 prostate carcinoma cell transmigration of an extracellular matrix in vitro, and that this increased invasiveness was independent of proteolytic degradation of the… (More)
DOI: 10.1007/BF00123400

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