EGF , epithelium and Developmentally regulated chromatin structure in c-fos 279 Characterisation of developmentally regulated chromatin structure in the coding region of the proto-oncogene , c-fos , in the male laboratory mouse

In mouse, tissue-specific developmental de novo methylation of the proto-oncogene cfos, which is abundantly expressed during embryonic stages, occurs perinatally (between the day of birth to 20 dpp) and is maintained in the adult. In liver, where c-fos is only active up to the day of birth, the gene has more sites methylated than in brain, where it is… CONTINUE READING