EFNS guidelines on the Clinical Management of Amyotrophic Lateral Sclerosis (MALS) – revised report of an EFNS task force

@article{Andersen2012EFNSGO,
  title={EFNS guidelines on the Clinical Management of Amyotrophic Lateral Sclerosis (MALS) – revised report of an EFNS task force},
  author={Peter Munch Andersen and Sharon Abrahams and Gian Domenico Borasio and Mamede de Carvalho and Adriano Chi{\`o} and Philip van Damme and Orla Hardiman and Katja Kollewe and Karen E. Morrison and Susanne Petri and Pierre Pradat and Vincenzo Silani and Barbara Tomik and Maria Wasner and Markus Weber},
  journal={European Journal of Neurology},
  year={2012},
  volume={19}
}
Background:  The evidence base for the diagnosis and management of amyotrophic lateral sclerosis (ALS) is weak. 

Paper Mentions

Interventional Clinical Trial
This study evaluated the influence of a tailored aerobic exercise protocol on the functional outcome in ALS patients. In addition, the investigators compare some CPET variables… Expand
ConditionsAmyotrophic Lateral Sclerosis
InterventionOther
Improving symptom management for people with amyotrophic lateral sclerosis
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This work aims to report the prevalence of ALS‐related symptoms and characterize self-reported symptomatic management, and to characterize self‐reported symptodic management. Expand
Evaluation of the application of the European guidelines for the diagnosis and clinical care of amyotrophic lateral sclerosis (ALS) patients in six French ALS centres
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Evaluated the extent to which the 2005 recommendations of the European Federation of Neurological Sciences on the multidisciplinary management of amyotrophic lateral sclerosis are followed in clinical practice. Expand
A Look at the Diversity in Management of Respiratory Failure in Amyotrophic Lateral Sclerosis
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A prospective study of medically stable subjects with amyotrophic lateral sclerosis to determine possible clinical or functional predictors of need for noninvasive ventilation (NIV) during an acute lower respiratory tract infection. Expand
Amyotrophic Lateral Sclerosis (ALS) Genetic Testing
  • 2019
Most cases of suspected ALS are diagnosed based on a unique combination of symptoms and the exclusion of similar disorders. The Escorial Criteria were developed in 2000 to standardize the clinicalExpand
Canadian best practice recommendations for the management of amyotrophic lateral sclerosis
KEY POINTS Amyotrophic lateral sclerosis (ALS) is a debilitating, progressive disease with degeneration of motor neurons in the brain and spinal cord causing weakness, muscle atrophy, fasciculationsExpand
Patients with sporadic and familial amyotrophic lateral sclerosis found value in genetic testing
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This research presents a novel probabilistic procedure that allows for the selection of a single gene for the treatment of ALS in patients with a history of multiple sclerosis. Expand
Multidisciplinary care in amyotrophic lateral sclerosis: a 4-year longitudinal observational study.
Over a four-year period, ALS patients complied with the modalities of the multidisciplinary management follow-up without any drop-outs. The multidisciplinary management structure also contributes toExpand
Neck flexor weakness at diagnosis predicts respiratory impairment in amyotrophic lateral sclerosis
The purpose was to assess the prognostic role of neck muscle weakness at diagnosis in amyotrophic lateral sclerosis (ALS) patients with respect to survival and respiratory impairment.
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The care of a patient with amyotrophic lateral sclerosis is complex and involved a wide multidisciplinary team, and recent guidelines in the UK look at the recommendations and implications for practice. Expand
Amyotrophic lateral sclerosis mimic syndromes
  • M. Ghasemi
  • Medicine
  • Iranian journal of neurology
  • 2016
TLDR
Some of the important mimics of ALS are discussed and potentially curative treatments exist for certain ALS mimic syndromes, but delay in starting these therapies may have an unfavorable effect on outcome. Expand
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The functional status of patients immediately before death was determined and the causes of death and the circumstances surrounding death in 302 patients with amyotrophic lateral sclerosis were investigated. Expand
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This data indicates that anxiety is a major risk factor for depression in patients with amyotrophic lateral sclerosis and the use of medication to treat anxiety is recommended. Expand
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Modafinil (Provigil) may be a helpful pharmacologic treatment for amyotrophic lateral sclerosis and palliative care measures, such as noninvasive ventilation and high-frequency chest wall oscillation, may also reduce fatigue. Expand
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A summary of the current research into the rehabilitation of ALS, including the role of exercise, spasticity management, mood disorders, pain, and palliative care is provided. Expand
EFNS task force on management of amyotrophic lateral sclerosis: guidelines for diagnosing and clinical care of patients and relatives
TLDR
Early diagnosis should be pursued and a number of investigations should be performed with high priority, and every effort should be made to maintain patient autonomy during the entire course of the disease. Expand
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