Corpus ID: 77292018

EFICACIA DE LA CARBOXIMETILCELULOSA SÓDICA PARA EL TRATAMIENTO DEL SÍNDROME DEL OJO SECO EFFICACY OF SODIUM CARBOXYMETHYLCELLULOSE IN THE TREATMENT OF DRY EYE SYNDROME

@inproceedings{Bruix2006EFICACIADL,
  title={EFICACIA DE LA CARBOXIMETILCELULOSA S{\'O}DICA PARA EL TRATAMIENTO DEL S{\'I}NDROME DEL OJO SECO EFFICACY OF SODIUM CARBOXYMETHYLCELLULOSE IN THE TREATMENT OF DRY EYE SYNDROME},
  author={A. Bruix and A. Adan and Casaroli-Marano Rp},
  year={2006}
}
Aim: To assess the efficacy of sodium carboxymethylcellulose in the treatment of dry eye. Material and methods: We carried out a prospective, randomized, masked-observer, control/problem group, single-center clinical assay during a period of 12 months in 19 patients that presented mild or moderate forms of dry eye. Patients were clinically evaluated each 3 months and treated with a 0.5% isotonic solution of sodium carboxymethylcellulose (CMC) or balanced salt solution. Subjective symptoms… Expand

References

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Unpreserved Carboxymethylcellulose Artificial Tears Evaluated in Patients with Keratoconjunctivitis Sicca
TLDR
The observed therapeutic value of unpreserved CMC-based artificial tears is supported and the possible reversal of squamous metaplasia in patients with KCS is suggested. Expand
Effect of carmellose-based artificial tears on the ocular surface in eyes after laser in situ keratomileusis.
TLDR
Postoperative and intraoperative use of carmellose-based artificial tears resulted in significantly more rapid recovery of the ocular surface after LASIK when compared to balanced salt solution. Expand
Carbomer- versus cellulose-based artificial-tear formulations: morphologic and toxicologic effects on a corneal cell line.
TLDR
Questions about the benefits of using high-viscosity gels in the treatment of dry-eye syndrome still remain and in the in vitro study, CMC artificial tears are less toxic than carbomer gel formulations. Expand
An electrolyte-based solution that increases corneal glycogen and conjunctival goblet-cell density in a rabbit model for keratoconjunctivitis sicca.
TLDR
The electrolyte-based solution is the first treatment to increase corneal glycogen and conjunctival goblet cells in a rabbit model of KCS, and it is shown that elevated tear osmolarity and sodium in eyes treated with this solution increased significantly relative to untreated KCS controls. Expand
Dry eye diagnosis and management in 2004
TLDR
Restasis shows promise as the first of these agents to be approved as therapy to treat moderate to severe dry eye disease, defined as an abnormality of tear film resulting in changes in the ocular surface. Expand
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TLDR
There is a need for standardization of disease terminology and diagnostic tests in order to improve the usefulness of epidemiological and clinical investigation of this important ocular disorder. Expand
Advances in the diagnosis and management of keratoconjunctivitis sicca.
TLDR
The findings indicate that keratoconjunctivitis sicca may represent a chronic wound-healing response to a poorly lubricated and inflamed ocular surface. Expand
Artificial Tear Composition and Promotion of Recovery of the Damaged Corneal Epithelium
TLDR
The ability of artificial tear solutions to promote recovery of the corneal epithelial barrier was determined by measurement ofCorneal uptake of 5,6 carboxyfluorescein (CF) by studying the effects of exposure to isotonic and nonpreserved solutions in severe dry eye syndromes. Expand
Ocular Surface Residence Times of Artificial Tear Solutions
TLDR
Dilute sodium hyaluronate (SH) solutions exhibit non-Newtonian rheology with high viscosities at low shear rates, which would be expected to enhance their ocular surface residence time. Expand
The treatment of dry eye.
TLDR
The most widely used therapy for dry eye disease is tear replacement by topical artificial tears, and topical anti-inflammatory and immunomodulatory agents are under investigation in the treatment of dry eye, as it is anticipated that they will correct the vicious cycle of inflammation and cell damage on the ocular surface and lacrimal glands. Expand
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