• Corpus ID: 55492925

EFFECTS OF TWO IMIDAZOLINE RECEPTOR ANTAGONISTS IN SPONTANEOUS BEHAVIOUR IN RATS

@inproceedings{Rusu2015EFFECTSOT,
  title={EFFECTS OF TWO IMIDAZOLINE RECEPTOR ANTAGONISTS IN SPONTANEOUS BEHAVIOUR IN RATS},
  author={Gabriela Rusu and Cătălina Elena Lupușoru and Liliana Mititelu Tarțău and Grațiela Eliza Popa and Nela Bibire and Raoul Vasile Lupușoru and Mihai Nechifor},
  year={2015}
}
We aimed to investigate the effects of imidazoline receptor antagonists’ idazoxan and efaroxan on spontaneous behaviour in rats. Rats were treated intraperitoneally with single doses of either idazoxan (1 mg/kgbw) and efaroxan (3 mg/kgbw) or distilled water (0.3 mL/ 100 g body weight). Locomotor activity and exploratory behaviour of the animals were evaluated using the LE-8811 Actimeter PanLAB device in order to count the number of horizontal, vertical and stereotypic movements. The data were… 

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