EFFECTS OF TRIPARANOL (MER-29) ON CHOLESTEROL BIOSYNTHESIS AND ON BLOOD STEROL LEVELS IN MAN.

@article{Steinberg1961EFFECTSOT,
  title={EFFECTS OF TRIPARANOL (MER-29) ON CHOLESTEROL BIOSYNTHESIS AND ON BLOOD STEROL LEVELS IN MAN.},
  author={Daniel Steinberg and Joel Avigan and E B Feigelson},
  journal={The Journal of clinical investigation},
  year={1961},
  volume={40 5},
  pages={
          884-93
        }
}
The possibility of reducing elevated blood cholesterol levels with agents that inhibit endogenous biosynthesis of cholesterol is an attractive one, since dietary treatment is sometimes difficult to achieve and almost always difficult to maintain. Some of the theoretical aspects of such an approach have been outlined (3, 4), and the feasibility of the approach has been established in experimental animals. For example, it has been shown that A4-cholestenone, a potent inhibitor of cholesterol… CONTINUE READING

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1 Excerpt

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