EFFECTS OF TIME OF ADMINISTRATION AND DIETARY IODINE LEVELS ON POTASSIUM IODIDE (KI) BLOCKADE OF THYROID IRRADIATION BY 131I FROM RADIOACTIVE FALLOUT

@article{Zanzonico2000EFFECTSOT,
  title={EFFECTS OF TIME OF ADMINISTRATION AND DIETARY IODINE LEVELS ON POTASSIUM IODIDE (KI) BLOCKADE OF THYROID IRRADIATION BY 131I FROM RADIOACTIVE FALLOUT},
  author={P. Zanzonico and D. Becker},
  journal={Health Physics: The Radiation Safety Journal},
  year={2000},
  volume={78},
  pages={660-667}
}
Abstract—Radioiodines, particularly 131I, may be released into the environment in breach-of-containment nuclear reactor accidents and localize in and irradiate the thyroid with an attendant risk of neoplastic growth and other adverse health effects. Pharmacologic thyroid blockade by oral potassium iodide (KI) (50–100 mg in adults) can substantially reduce thyroid uptake of and irradiation by internalized radioiodine. In the current analysis, computer modeling of iodine metabolism has been used… Expand
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