EFFECT OF MULTIPLICITY OF INFECTION ON NEWCASTLE DISEASE VIRUS-HELA CELL INTERACTION

@article{Wheelock1961EFFECTOM,
  title={EFFECT OF MULTIPLICITY OF INFECTION ON NEWCASTLE DISEASE VIRUS-HELA CELL INTERACTION},
  author={E. Frederick Wheelock and I. I. Tamm},
  journal={The Journal of Experimental Medicine},
  year={1961},
  volume={113},
  pages={317 - 338}
}
The effects of a hundred-fold difference in virus/cell multiplicity on the interaction of Newcastle disease virus (NDV) with HeLa cells were studied, and various phases of the virus reproductive cycle were related to cellular consequences of infection. At both multiplicities used all cells were infected. The following events occurred 1 to 2 hours earlier in cells which were inoculated with the higher multiplicity: (a) first appearance of newly made virus antigen, and the amount present at any… CONTINUE READING

References

Publications referenced by this paper.
SHOWING 1-10 OF 26 REFERENCES

Characterization of HeLa cell-derived Newcastle disease virus

P. I. Marcus
  • (NDV), Bact. Proc.,
  • 1960
VIEW 1 EXCERPT

Site of intracellular antigen production by myxoviruses.

  • Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine
  • 1960
VIEW 1 EXCERPT

The induction of amitotic nuclear division by pseudorabies virus multiplying in single rabbit kidney cells, Virology

M. Reissig, A. S. Kaplan
  • 1960
VIEW 1 EXCERPT

Quantitative aspects of an in vitro virus-induced toxic reaction. I. General aspects of the reaction of Newcastle disease virus with L cells, Virology

W. C. Wilcox
  • 1959
VIEW 1 EXCERPT