EFFECT OF ACETAZOLAMIDE ON EXERCISE PERFORMANCE AND MUSCLE MASS AT HIGH ALTITUDE

@article{Bradwell1986EFFECTOA,
  title={EFFECT OF ACETAZOLAMIDE ON EXERCISE PERFORMANCE AND MUSCLE MASS AT HIGH ALTITUDE},
  author={Arthur R Bradwell and PeterW. Dykes and John H. Coote and Peter J. G. Forster and James Milles and IanM. Chesner and Nicholas Edward Richardson},
  journal={The Lancet},
  year={1986},
  volume={327},
  pages={1001-1005}
}
The effect of acetazolamide (Az) on exercise performance and muscle mass in acclimatised subjects at an altitude of 4846 m was assessed in 11 subjects and compared with the effect of placebo on 10 other subjects. Exercise performance at 85% maximum heart rate fell by 37% in the Az group and by 45% in controls (p less than 0.05). Weight loss was greater in the placebo group at high altitude (p less than 0.01) and this correlated with the fall in exercise performance (p less than 0.001). During… CONTINUE READING
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