EFCBP1/NECAB1, a brain-specifically expressed gene with highest abundance in temporal lobe, encodes a protein containing EF-hand and antibiotic biosynthesis monooxygenase domains.

@article{Wu2007EFCBP1NECAB1AB,
  title={EFCBP1/NECAB1, a brain-specifically expressed gene with highest abundance in temporal lobe, encodes a protein containing EF-hand and antibiotic biosynthesis monooxygenase domains.},
  author={Hai Lang Wu and Dan Li and Yuxi Shan and B. H. Wan and Saiyin Hexige and Jinhu Guo and Chaoqun Wu and Long Yu},
  journal={DNA sequence : the journal of DNA sequencing and mapping},
  year={2007},
  volume={18 1},
  pages={73-9}
}
Human EFCBP/NECAB family consists of important participants in neuronal calcium signaling, including EFCBP1/NECAB1, EFCBP2/NECAB2 and EFCBP3/NECAB3. In the present study, we identified the full-length 5229 bp EFCBP1 cDNA which was not described before. Human EFCBP1 encodes a 351 amino acid protein containing two EF-hand motifs and an antibiotic biosynthesis monooxygenase (ABM) domain, sharing 49.9 and 56.8% global homology with human EFCBP2 and EFCBP3. Northern hybridization revealed that… CONTINUE READING