EDTA treatment of intermittent claudication--a double-blind, placebo-controlled study.

@article{Guldager1992EDTATO,
  title={EDTA treatment of intermittent claudication--a double-blind, placebo-controlled study.},
  author={Bernadette Guldager and R Jelnes and S. J\orgensen and Jeppe Sylvest Nielsen and Anette Klaerke and K Mogensen and Karin E. Larsen and Eleanor J Reimer and Jakob Holm and S Ottesen},
  journal={Journal of internal medicine},
  year={1992},
  volume={231 3},
  pages={261-7}
}
A double-blind, randomized multicentre study was undertaken to evaluate the possible effect of chelation treatment with ethylenediamine-tetraacetic acid (EDTA) in patients with severe intermittent claudication. A total of 153 patients received 20 intravenous infusions of either 3 g Na2EDTA or placebo during a period of 5-9 weeks. Vitamin, mineral and trace element supplements were administered orally. The changes observed in the pain-free and maximal walking distances, measured on a treadmill… CONTINUE READING