EDTA stimulates cleavage stage bovine embryo development in culture but inhibits blastocyst development and differentiation.

@article{Gardner2000EDTASC,
  title={EDTA stimulates cleavage stage bovine embryo development in culture but inhibits blastocyst development and differentiation.},
  author={David K Gardner and Michael W. Lane},
  journal={Molecular reproduction and development},
  year={2000},
  volume={57 3},
  pages={256-61}
}
Culture of bovine zygotes in medium SOFaa supplemented with 100 microM EDTA significantly increased cleavage rates during the first 72 hr of development compared to development in SOFaa. However, continued culture in the presence of EDTA for a further 72 hr (total of 6 days of culture) resulted in significantly reduced development to the morulae/blastocyst and blastocyst stages compared to culture without EDTA. Highest rates of development to the morulae/blastocyst stage (56.5%) and to the… CONTINUE READING

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