ECG telemetry in conscious guinea pigs.

@article{Ruppert2016ECGTI,
  title={ECG telemetry in conscious guinea pigs.},
  author={Sabine Ruppert and Thomas Vormberge and B. R. Igl and Michael C. Hoffmann},
  journal={Journal of pharmacological and toxicological methods},
  year={2016},
  volume={81},
  pages={
          88-98
        }
}
INTRODUCTION During preclinical drug development, monitoring of the electrocardiogram (ECG) is an important part of cardiac safety assessment. To detect potential pro-arrhythmic liabilities of a drug candidate and for internal decision-making during early stage drug development an in vivo model in small animals with translatability to human cardiac function is required. METHODS Over the last years, modifications/improvements regarding animal housing, ECG electrode placement, and data… CONTINUE READING
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