EBV-specific immune responses in patients with multiple sclerosis responding to IFNβ therapy.


BACKGROUND Symptomatic primary infection with the human γ-herpesvirus Epstein-Barr virus (EBV) and elevated immune responses to EBV are associated with the development and progression of multiple sclerosis (MS). Interferon-beta (IFNβ), first-line treatment for relapse-onset MS, exhibits complex immunoregulatory and antiviral activities. OBJECTIVE To… (More)
DOI: 10.1177/1352458511426816


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