EBV-inducing factor from platelets exhibits growth-promoting activity for NIH 3T3 cells.

@article{Bauer1985EBVinducingFF,
  title={EBV-inducing factor from platelets exhibits growth-promoting activity for NIH 3T3 cells.},
  author={Gerrit E.W. Bauer and Ulf Birnbaum and Prof. Dr. med. W. H{\"o}fler and C-H. Heldin},
  journal={The EMBO journal},
  year={1985},
  volume={4 8},
  pages={
          1957-61
        }
}
An Epstein-Barr virus-indicating factor (EIF) has been purified from serum and platelets. We show here that highly purified preparations of platelet EIF exhibit growth-promoting activity for NIH 3T3 cells maintained in platelet-poor plasma. The Epstein-Barr virus (EBV)-inducing activity and growth-promoting activity co-elute upon gel chromatography under non-dissociating as well as dissociating conditions and co-migrate in SDS-gel electrophoresis, supporting the notion that both activities… CONTINUE READING
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