EBV+ diffuse large B-cell lymphoma arising within atrial myxoma. An example of a distinct primary cardiac EBV+ DLBCL of immunocompetent patients.

@article{Svec2012EBVDL,
  title={EBV+ diffuse large B-cell lymphoma arising within atrial myxoma. An example of a distinct primary cardiac EBV+ DLBCL of immunocompetent patients.},
  author={Alexandr Svec and Madhusudan Rangaiah and Montserrat Giles and Radek Jak{\vs}a and Karen A. McAulay},
  journal={Pathology, research and practice},
  year={2012},
  volume={208 3},
  pages={172-6}
}
Cardiac myxoma and diffuse large B-cell lymphoma are uncommon tumors, yet four composite tumors have been reported since 2009. We are reporting on the fifth case providing detailed immunohistochemical and FISH analyses. The lymphoma was present as superficially located nests of large cells with patchy necrosis in the background of a typical atrial myxoma. It displayed features of DLBCL with non-germinal center phenotype, expressed EBER, LMP1, EBNA2 and shared the following features with the… CONTINUE READING

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