EAACI/GA2LEN/EDF/WAO guideline: definition, classification and diagnosis of urticaria

@article{Zuberbier2009EAACIGA2LENEDFWAOGD,
  title={EAACI/GA2LEN/EDF/WAO guideline: definition, classification and diagnosis of urticaria},
  author={Torsten Zuberbier and Riccardo Asero and Carsten Bindslev‐Jensen and Giorgio Walter Canonica and Martin K. Church and Ana Mar{\'i}a Gim{\'e}nez-Arnau and Clive E Grattan and Alexander Kapp and H. F. Merk and Barbara Rogala and Sarbjit S. Saini and Mario Sanchez‐Borges and Peter Schmid‐Grendelmeier and Holger J. Schünemann and Petra Staubach and G. A. Vena and Bettina Wedi and M. Maurer},
  journal={Allergy},
  year={2009},
  volume={64}
}
This guideline, together with its sister guideline on the management of urticaria [Zuberbier T, Asero R, Bindslev‐Jensen C, Canonica GW, Church MK, Giménez‐Arnau AM et al. EAACI/GA²LEN/EDF/WAO Guideline: Management of urticaria. Allergy, 2009; 64:1427–1443] is the result of a consensus reached during a panel discussion at the 3rd International Consensus Meeting on Urticaria, Urticaria 2008, a joint initiative of the Dermatology Section of the European Academy of Allergology and Clinical… 

EAACI/GA²LEN/EDF/WAO guideline: management of urticaria

TLDR
This guideline has a profound impact on the quality of life and effective treatment is, therefore, required and the recommended first line treatment is new generation, nonsedating H1‐antihistamines, and second‐line therapies should be added to the antihistamine treatment.

/ GA 2 LEN / EDF / WAO guideline for the definition , classification , diagnosis and management of urticaria

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This guideline outlines evidence-based diagnostic and therapeutic approaches for the different subtypes of urticaria, taking into account the recent progress in identifying its causes, eliciting factors and pathomechanisms.

The EAACI/GA²LEN/EDF/WAO guideline for the definition, classification, diagnosis and management of urticaria

TLDR
This guideline covers the definition and classification of urticaria, taking into account the recent progress in identifying its causes, eliciting factors and pathomechanisms, and outlines evidence‐based diagnostic and therapeutic approaches for the different subtypes ofUrticaria.

The EAACI/GA(2) LEN/EDF/WAO Guideline for the definition, classification, diagnosis, and management of urticaria: the 2013 revision and update.

TLDR
This guideline covers the definition and classification of urticaria, taking into account the recent progress in identifying its causes, eliciting factors and pathomechanisms, and outlines evidence-based diagnostic and therapeutic approaches for the different subtypes ofUrticaria.

The definition and diagnostic testing of physical and cholinergic urticarias – EAACI/GA2LEN/EDF/UNEV consensus panel recommendations

TLDR
The recommendations for the definition and diagnosis presented in this position paper are the result of a panel consensus meeting held in December 2008 in Berlin and acknowledge the latest changes in the understanding of physical urticarias and cholinergic urticaria as well as the recent development of novel diagnostic tools.

A Comparison of the United States and International Perspective on Chronic Urticaria Guidelines.

Methods report on the development of the 2013 revision and update of the EAACI/GA2 LEN/EDF/WAO guideline for the definition, classification, diagnosis, and management of urticaria.

TLDR
This guideline covers the definition and classification of urticaria, taking into account the recent progress in identifying its causes, eliciting factors and pathomechanisms, and outlines evidence-based diagnostic and therapeutic approaches for the different subtypes of Urticaria.

Review and Perspectives of the Recent International Guidelines on Treatment of Chronic Urticaria

TLDR
The most recent version of the EAACI/GA2LEN/EDF/WAO guideline outlines definitions as well as diagnostic and treatment strategies for urticaria and its subtypes, with many areas of consensus.

Teil 1: Klassifikation und Diagnostik der Urtikaria - deutschsprachige Version der internationalen S3-Leitlinie*

TLDR
This German language guideline covers the definition and classification of urticaria, taking into account the recent progress in identifying its causes, eliciting factors, and pathomech-anisms, and outlines evidence-based approaches to economical diagnosis for different sub-types of Urticaria.

Towards rationalizing the nomenclature and classification of urticaria: some guidance on guidelines

  • C. Grattan
  • Medicine
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology
  • 2007
TLDR
This issue of Clinical and Experimental Allergy sees the publication of a third set of national or international guidelines on urticaria in the English language within Europe since 2001, and a number of anomalies relating to the nomenclature and classification have emerged.
...

References

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EAACI/GA2LEN/EDF guideline: definition, classification and diagnosis of urticaria

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This guideline covers the definition and classification of urticaria, taking into account the recent progress in identifying causes, eliciting factors and pathomechanisms of this disease.

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Acute urticaria in either adults or children is a rarity in the authors' practice, and it is surmise that most of these are dealt with in a primary care or district general hospital setting.

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The present review serves to address urticaria – both acute and chronic – as well as the differential diagnosis of urticarial syndromes in the pediatric population, and to update the reader on progress in the pathophysiology, diagnosis and treatment of uricaria.

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A consensus definition and classification of the disease and its subtypes, taking into account new developments, are needed and a guideline for diagnostic procedures in different subtypes of urticaria is provided.

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The arguments for an important role of underlying causal infections in chronic urticaria are weak, from an evidence-based viewpoint, but there are data suggesting a link.

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TLDR
Despite all cases with physical urticaria having been excluded, physical factors such as exercise were considered by 20% to make the urticarial attacks worse and food was mentioned as a factor worsening the weals by 30% and drinks by 18%.

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An additive-free, stringently controlled diet provides a simple means of diagnosing and treating the majority of patients with chronic urticaria, and shows complete remission on diet and lasting improvement in all but one of the remaining patients on diet.

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TLDR
Both the autoantibody levels and the functional basophil phenotype remained stable in subjects with active disease, whereas there was an enhancement in basophils function as subjects evolved into a state of remission, which appears independent of the presence of autoantIBody.

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The results indicate that clinical and etiologic features of urticaria in infants are somewhat different from those of adults and children.

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TLDR
The parameters of the ASST are determined which define the optimal sensitivity and specificity for the identification of patients with autoantibodies and the following subjects had positive ASSTs: none of 15 dermographics, none of 10 atopics, one of nine cholinergics and one of 40 controls.
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