E74-like factor 2 regulates valosin-containing protein expression.

  title={E74-like factor 2 regulates valosin-containing protein expression.},
  author={Binglin Zhang and Yasuhiko Tomita and Ying Qiu and Juxiang He and Eiichi Morii and Shinzaburo Noguchi and Katsuyuki Aozasa},
  journal={Biochemical and biophysical research communications},
  volume={356 3},
Enhanced expression of valosin-containing protein (VCP) correlates with invasion and metastasis of cancers. To clarify the transcription mechanism of VCP, human and mouse genomic sequence was compared, revealing a 260 bp DNA sequence in the 5'-flanking region of VCP gene to be highly conserved between the two, in which binding motif of E74-like factor 2/new… CONTINUE READING