E3 ubiquitin ligase activity and targeting of BAT3 by multiple Legionella pneumophila translocated substrates.

@article{Ensminger2010E3UL,
  title={E3 ubiquitin ligase activity and targeting of BAT3 by multiple Legionella pneumophila translocated substrates.},
  author={Alexander W Ensminger and Ralph R Isberg},
  journal={Infection and immunity},
  year={2010},
  volume={78 9},
  pages={3905-19}
}
The intracellular bacterial pathogen Legionella pneumophila modulates a number of host processes during intracellular growth, including the eukaryotic ubiquitination machinery, which dictates the stability, activity, and/or localization of a large number of proteins. A number of L. pneumophila proteins contain eukaryotic-like motifs typically associated… CONTINUE READING