E2F integrates cell cycle progression with DNA repair, replication, and G(2)/M checkpoints.

@article{Ren2002E2FIC,
  title={E2F integrates cell cycle progression with DNA repair, replication, and G(2)/M checkpoints.},
  author={Bing Ren and Hieu T. Cam and Yasuhiko Takahashi and Thomas Volkert and Jolyon Terragni and Richard A. Young and Brian D. Dynlacht},
  journal={Genes & development},
  year={2002},
  volume={16 2},
  pages={
          245-56
        }
}
The E2F transcription factor family is known to play a key role in the timely expression of genes required for cell cycle progression and proliferation, but only a few E2F target genes have been identified. We explored the possibility that E2F regulators play a broader role by identifying additional genes bound by E2F in living human cells. A protocol was developed to identify genomic binding sites for DNA-binding factors in mammalian cells that combines immunoprecipitation of cross-linked… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 495 CITATIONS

Kinetochore genes are coordinately up-regulated in human tumors as part of a FoxM1-related cell division program

  • Molecular biology of the cell
  • 2014
VIEW 5 EXCERPTS
CITES BACKGROUND, RESULTS & METHODS
HIGHLY INFLUENCED

Emerging links between E2F control and mitochondrial function.

VIEW 4 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Role of NEK2A in Human Cancer and Its Therapeutic Potentials

  • BioMed research international
  • 2015
VIEW 4 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

An E2F1-Mediated DNA Damage Response Contributes to the Replication of Human Cytomegalovirus

  • PLoS pathogens
  • 2011
VIEW 9 EXCERPTS
CITES BACKGROUND & METHODS
HIGHLY INFLUENCED

FILTER CITATIONS BY YEAR

2002
2019

CITATION STATISTICS

  • 38 Highly Influenced Citations

  • Averaged 22 Citations per year over the last 3 years

  • 2% Increase in citations per year in 2018 over 2017

References

Publications referenced by this paper.
SHOWING 1-10 OF 37 REFERENCES

Similar Papers

Loading similar papers…