E1AF expression is associated with extra-prostatic growth and matrix metalloproteinase-7 expression in prostate cancer.

@article{Maruta2009E1AFEI,
  title={E1AF expression is associated with extra-prostatic growth and matrix metalloproteinase-7 expression in prostate cancer.},
  author={Sugure Maruta and Hideki Sakai and Shigeru Kanda and Tomayoshi Hayashi and Hiroshi Kanetake and Yasuyoshi Miyata},
  journal={APMIS : acta pathologica, microbiologica, et immunologica Scandinavica},
  year={2009},
  volume={117 11},
  pages={791-6}
}
E1AF is associated with malignant aggressiveness via regulation of matrix metalloproteinases (MMPs), which play pivotal roles in invasion through the degradation of extracellular matrix of tissues surrounding tumors. However, the clinical significance of E1AF and MMPs in patients with prostate cancer is not fully understood. We reviewed 50 tissue samples from patients with T2-3N0M0 prostate cancer who had undergone radical operation. Expression levels of E1AF, MMP-1, -3, -7, -9 and -14 were… CONTINUE READING
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