E. coli uvrB protein binds to DNA in the presence of uvrA protein


In vivo and in vitro, the endonucleolytic incision of damaged DNA containing pyrimidine dimers or other bulky lesions requires the action of the uvrA, uvrB and uvrC gene products of Escherichia coli1–3. To understand better how the products of these three genes mediate incision, all three genes have been cloned4–10. Although the gene products of the three… (More)
DOI: 10.1038/294480a0


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