E. coli integration host factor binds to specific sites in DNA.

  title={E. coli integration host factor binds to specific sites in DNA.},
  author={Nancy L. Craig and Howard A. Nash},
  volume={39 3 Pt 2},
E. coli integration host factor (IHF) both participates directly in phage lambda site-specific recombination and regulates the expression of phage and bacterial genes. Using protection from nuclease and chemical attack as an assay, we examined the interaction of IHF with DNA. We found that IHF is a specific DNA binding protein that interacts with three distinct segments of attP, the recombination site carried by phage lambda. We also found that specific IHF binding sites are located in non-att… CONTINUE READING
73 Citations
45 References
Similar Papers


Publications citing this paper.
Showing 1-10 of 73 extracted citations


Publications referenced by this paper.
Showing 1-10 of 45 references

Regulation of flagellin gene expressfon by integration host factor

  • E. Szekely, H. Mfller, M. Simon
  • J. Bactenol.,
  • 1984
Highly Influential
7 Excerpts

Site-speciftc DNA condensation and pairtng medlated by the Int protein of bacteriophage X

  • M. Better, C. Lu, R. Willlams, H. Echols
  • Proc. Nat Acad. SCI. USA
  • 1982
Highly Influential
4 Excerpts

lnteractfon of Int protern wrth speciffc sates on h att DNA

  • W. Ross, A. Landy, Y Kfkuchi., H. Nash
  • Cell
  • 1979
Highly Influential
4 Excerpts

Multi-level regulation of bacteriophage X lysogeny by the E. coli

  • H. Miller
  • himA gene. Cell
  • 1981
Highly Influential
4 Excerpts

The phage h aft site functlonal limits and interactton with lnt protein

  • Hsu, PAL, W Ross, A Landy
  • Nature 285,
  • 1980
Highly Influential
5 Excerpts

3-A resolutron structure of a protein with histone-lfke properties in prokaryotes

  • I. Tanaka, Appelt, J.K.. Drjk, S. W. Whfte, K. S. Wilson
  • Nature 370,
  • 1984
2 Excerpts

An E. co/i mutant unable to support sate-specffic recombination of bacteriophage A

  • A. Kikuchi, E. Flamm, R. Weisberg
  • J. Mol. Biol.
  • 1984
1 Excerpt

Kinked DNA tn crystalline complex with EcoRl endonuclease

  • C Frederick, Grable, +6 authors J. Rosenberg
  • Nature 309,
  • 1984
2 Excerpts

Primary structure of the h / p gene of E . cob and of Its product , the p subunlt of Integration host factor J . Mol . Btol .

  • E Flamm, R. Weksberg
  • 1984

Primary structure of the h/p gene of E. cob and of Its product, the p subunlt of Integration host factor

  • E Flamm, R. Weksberg
  • J. Mol. Btol.,
  • 1984

Similar Papers

Loading similar papers…