E-cadherin genetic variants predict survival outcome in breast cancer patients

Abstract

E-cadherin is a major component of adherens junctions that regulates cell shape and maintains tissue integrity. A complete loss or any decrease in cell surface expression of E-cadherin will interfere with the cell-to-cell junctions’ strength and leads to cell detachment and escape from the primary tumor site. In this prospective study, three functional… (More)
DOI: 10.1186/s12967-016-1077-4

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Cite this paper

@inproceedings{Memni2016EcadherinGV, title={E-cadherin genetic variants predict survival outcome in breast cancer patients}, author={Hager Memni and Yosra Macherki and Zahra Klayech and Ahlem Ben-Haj-Ayed and Karim Hamda Farhat and Yassmine Remadi and Sallouha Gabbouj and Wijden Mahfoudh and Nadia Bouzid and Noureddine Bouaouina and Lotfi Chouchane and Abdelfattah Zakhama and Elham Hassen}, booktitle={Journal of Translational Medicine}, year={2016} }