E-cadherin expression associated with differentiation and prognosis in patients with non-small cell lung cancer.

@article{Liu2001EcadherinEA,
  title={E-cadherin expression associated with differentiation and prognosis in patients with non-small cell lung cancer.},
  author={Ding-yi Liu and Chao-Cheng Huang and Kotaro Kameyama and Eiichi Hayashi and Akira Yamauchi and Shoji Kobayashi and Hiroyasu Yokomise},
  journal={The Annals of thoracic surgery},
  year={2001},
  volume={71 3},
  pages={949-54; discussion 954-5}
}
BACKGROUND E-Cadherin plays a major role in maintaining the intercellular junctions in epithelial tissues. The reduction of E-cadherin expression in cancer cells may be associated with tumor differentiation, metastasis, and a poor prognosis. METHODS Immunohistochemistry for E-cadherin expression was performed on 109 tumors from patients with non-small cell lung cancer who underwent operations. RESULTS With respect to membranous immunostaining, 57 carcinomas were E-cadherin-positive, 39… CONTINUE READING