E and ID proteins branch out

@article{Kee2009EAI,
  title={E and ID proteins branch out},
  author={Barbara L Kee},
  journal={Nature Reviews Immunology},
  year={2009},
  volume={9},
  pages={175-184}
}
E and inhibitor of DNA binding (ID) proteins are transcriptional regulators that function in many developmental processes in vertebrates and invertebrates. One subset of E proteins, the E2A proteins, have a central role in the transcriptional regulatory networks that promote commitment to and differentiation of the B- and T-cell lineages, and their function in these lineages is modulated by ID proteins. In this Review, I discuss recent studies that reveal a more extensive role for E and ID… CONTINUE READING
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