E-Selectin expression in human endothelial cells exposed to PM10: the role of endotoxin and insoluble fraction.

@article{AlfaroMoreno2007ESelectinEI,
  title={E-Selectin expression in human endothelial cells exposed to PM10: the role of endotoxin and insoluble fraction.},
  author={Ernesto Alfaro-Moreno and Rebeca L{\'o}pez-Marure and Angelica Montiel-D{\'a}valos and Peter Symonds and {\'A}lvaro R. Osornio-Vargas and Irma Rosas and J. Clifford Murray},
  journal={Environmental research},
  year={2007},
  volume={103 2},
  pages={
          221-8
        }
}
Exposure to PM10 is associated with cardiovascular effects. We evaluated the effects of PM10 on E-Selectin expression and monocytic cell adhesion in human umbilical vein endothelial cells (HUVECs). HUVEC were exposed to PM10 (5-40 microg/cm2) for 6 h, following which surface E-Selectin expression was detected by fluorescence microscopy and flow cytometry. The effects of total particles, particles treated with polymixin-B to block the effects of endotoxin, and both soluble and insoluble… Expand
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