E Proteins and Id2 converge on p57Kip2 to regulate cell cycle in neural cells.

@article{Rothschild2006EPA,
  title={E Proteins and Id2 converge on p57Kip2 to regulate cell cycle in neural cells.},
  author={Gerson Rothschild and Xudong Zhao and Antonio Iavarone and Anna Lasorella},
  journal={Molecular and cellular biology},
  year={2006},
  volume={26 11},
  pages={4351-61}
}
A precise balance between proliferation and differentiation must be maintained during neural development to obtain the correct proportion of differentiated cell types in the adult nervous system. The basic helix-loop-helix (bHLH) transcription factors known as E proteins and their natural inhibitors, the Id proteins, control the timing of differentiation and terminal exit from the cell cycle. Here we show that progression into S phase of human neuroblastoma cells is prevented by E proteins and… CONTINUE READING
40 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 40 extracted citations

Similar Papers

Loading similar papers…