E‐Cadherin Transport from the trans‐Golgi Network in Tubulovesicular Carriers is Selectively Regulated by Golgin‐97
@article{Lock2005ECadherinTF, title={E‐Cadherin Transport from the trans‐Golgi Network in Tubulovesicular Carriers is Selectively Regulated by Golgin‐97}, author={John G. Lock and L. Hammond and F. Houghton and P. Gleeson and J. Stow}, journal={Traffic}, year={2005}, volume={6} }
E‐cadherin is a cell–cell adhesion protein that is trafficked and delivered to the basolateral cell surface. Membrane‐bound carriers for the post‐Golgi exocytosis of E‐cadherin have not been characterized. Green fluorescent protein (GFP)‐tagged E‐cadherin (Ecad‐GFP) is transported from the trans‐Golgi network (TGN) to the recycling endosome on its way to the cell surface in tubulovesicular carriers that resemble TGN tubules labeled by members of the golgin family of tethering proteins. Here, we… CONTINUE READING
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References
SHOWING 1-10 OF 53 REFERENCES
The GRIP Domain is a Specific Targeting Sequence for a Population of trans‐Golgi Network Derived Tubulo‐Vesicular Carriers
- Biology, Medicine
- Traffic
- 2001
- 59
Trafficking of Yellow‐Fluorescent‐Protein‐Tagged µ1 Subunit of Clathrin Adaptor AP‐1 Complex in Living Cells
- Biology, Medicine
- Traffic
- 2001
- 43
Rab11 in recycling endosomes regulates the sorting and basolateral transport of E-cadherin.
- Biology, Medicine
- Molecular biology of the cell
- 2005
- 349
- PDF
Mechanism of constitutive export from the golgi: bulk flow via the formation, protrusion, and en bloc cleavage of large trans-golgi network tubular domains.
- Biology, Medicine
- Molecular biology of the cell
- 2003
- 178
Mammalian GRIP domain proteins differ in their membrane binding properties and are recruited to distinct domains of the TGN
- Biology, Medicine
- Journal of Cell Science
- 2004
- 70
- PDF
Selective Delivery of Secretory Cargo in Golgi‐Derived Carriers of Nonepithelial Cells
- Biology, Medicine
- Traffic
- 2002
- 43
- PDF
Recycling endosomes can serve as intermediates during transport from the Golgi to the plasma membrane of MDCK cells
- Biology, Medicine
- The Journal of cell biology
- 2004
- 412
- PDF
Coupling Assembly of the E-Cadherin/β-Catenin Complex to Efficient Endoplasmic Reticulum Exit and Basal-lateral Membrane Targeting of E-Cadherin in Polarized MDCK Cells
- Biology, Medicine
- The Journal of cell biology
- 1999
- 312
- PDF
The Golgi-targeting sequence of the peripheral membrane protein p230.
- Biology, Medicine
- Journal of cell science
- 1999
- 71
- PDF
Visualization of TGN to endosome trafficking through fluorescently labeled MPR and AP-1 in living cells.
- Biology, Medicine
- Molecular biology of the cell
- 2003
- 181
- PDF