Dysregulation of uterine signaling pathways in progesterone receptor-Cre knockout of dicer.

@article{Hawkins2012DysregulationOU,
  title={Dysregulation of uterine signaling pathways in progesterone receptor-Cre knockout of dicer.},
  author={Shannon M Hawkins and Claudia V. Andreu-Vieyra and Tae Hoon Kim and Jae-Wook Jeong and Myles C. Hodgson and Ruihong Chen and Chad J Creighton and John P. Lydon and Preethi H. Gunaratne and Francesco J. Demayo and Martin M. Matzuk},
  journal={Molecular endocrinology},
  year={2012},
  volume={26 9},
  pages={1552-66}
}
Epithelial-stromal interactions in the uterus are required for normal uterine functions such as pregnancy, and multiple signaling pathways are essential for this process. Although Dicer and microRNA (miRNA) have been implicated in several reproductive processes, the specific roles of Dicer and miRNA in uterine development are not known. To address the roles of miRNA in the regulation of key uterine pathways, we generated a conditional knockout of Dicer in the postnatal uterine epithelium and… CONTINUE READING
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Dicer Is Crucial for Uterine Development Mol Endocrinol

  • WM Merritt, YG Lin, LY Han, AA Kamat, WA Spannuth, Hawkins Schmandt
  • N Engl J Med
  • 2012

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