Dysregulation of urinary miR-21 and miR-200b associated with interstitial fibrosis and tubular atrophy (IFTA) in renal transplant recipients.

@article{Vahed2017DysregulationOU,
  title={Dysregulation of urinary miR-21 and miR-200b associated with interstitial fibrosis and tubular atrophy (IFTA) in renal transplant recipients.},
  author={Sepideh Zununi Vahed and Yadollah Omidi and Mohammad Reza Ardalan and Nasser Samadi},
  journal={Clinical biochemistry},
  year={2017},
  volume={50 1-2},
  pages={32-39}
}
OBJECTIVE microRNAs (miRNAs) are endogenous gene expression regulators that are involved in renal function and physiopathology, making them potential biomarkers in the realm of transplantation. Here, we aimed to evaluate urinary miRNA expression levels and assess their possible values in the prospective evaluation of renal allograft function. DESIGN AND METHODS The expression levels of four miRNAs involved in renal fibrosis were quantified in urine cell pellets of 47 kidney recipients (with… CONTINUE READING
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