Dysregulation of the immune system in Aicardi-Goutières syndrome: another example in a TREX1-mutated patient.

@article{Olivieri2013DysregulationOT,
  title={Dysregulation of the immune system in Aicardi-Gouti{\`e}res syndrome: another example in a TREX1-mutated patient.},
  author={Ivana Olivieri and Marco Cattalini and Davide Tonduti and Roberta La Piana and Carla Luisa Uggetti and Jessica Galli and Antonella Meini and Anǵela Tincani and Daniele Moratto and Elisa Maria Fazzi and Umberto Balottin and Simona Orcesi},
  journal={Lupus},
  year={2013},
  volume={22 10},
  pages={
          1064-9
        }
}
Aicardi-Goutières syndrome (AGS) is a rare genetic encephalopathy characterized by neurological and extraneurological involvement. A clinical overlap between AGS and systemic lupus erythematosus (SLE) has been reported. We describe an AGS patient who developed autoimmune manifestations: thyroiditis, cANCA positivity, antiphospholipid antibodies and cerebral ischemia. This first description of antiphospholipid syndrome in a TREX1-mutated patient further expands the clinical spectrum of AGS… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-10 OF 10 CITATIONS

Similar Papers

Loading similar papers…