Dysregulation of the complement cascade in the hSOD1G93A transgenic mouse model of amyotrophic lateral sclerosis

@inproceedings{Lee2013DysregulationOT,
  title={Dysregulation of the complement cascade in the hSOD1G93A transgenic mouse model of amyotrophic lateral sclerosis},
  author={John D Lee and Nur A Kamaruzaman and Jenny N. T. Fung and Stephen M. Taylor and Bradley J. Turner and Julie D. Atkin and Trent M Woodruff and Peter G. Noakes},
  booktitle={Journal of Neuroinflammation},
  year={2013}
}
Components of the innate immune complement system have been implicated in the pathogenesis of amyotrophic lateral sclerosis (ALS); however, a comprehensive examination of complement expression in this disease has not been performed. This study therefore aimed to determine the expression of complement components (C1qB, C4, factor B, C3/C3b, C5 and CD88) and regulators (CD55 and CD59a) in the lumbar spinal cord of hSOD1G93A mice during defined disease stages. hSOD1G93A and wild-type mice were… CONTINUE READING
Highly Cited
This paper has 117 citations. REVIEW CITATIONS
Recent Discussions
This paper has been referenced on Twitter 4 times over the past 90 days. VIEW TWEETS

Citations

Publications citing this paper.
Showing 1-10 of 22 extracted citations

117 Citations

020406020142015201620172018
Citations per Year
Semantic Scholar estimates that this publication has 117 citations based on the available data.

See our FAQ for additional information.

References

Publications referenced by this paper.
Showing 1-10 of 57 references

Similar Papers

Loading similar papers…