Dysregulation of thalamic sensory ‘transmission’ in schizophrenia: neurochemical vulnerability to hallucinations

@article{Behrendt2006DysregulationOT,
  title={Dysregulation of thalamic sensory ‘transmission’ in schizophrenia: neurochemical vulnerability to hallucinations},
  author={R. Behrendt},
  journal={Journal of Psychopharmacology},
  year={2006},
  volume={20},
  pages={356 - 372}
}
  • R. Behrendt
  • Published 2006
  • Medicine, Psychology
  • Journal of Psychopharmacology
  • Cholinergic arousal mechanisms predispose thalamic and cortical neurons to fire action potentials at gamma rhythms, which have a tendency to resonate in thalamocortical networks, thereby forming coherent assemblies under constraints of sensory input to specific thalamic nuclei, on the one hand, and prefrontal and limbic attentional mechanisms, on the other. Perception may be based on sustained assemblies of coherent gamma oscillations in thalamocortical circuits. In schizophrenia, the impact of… CONTINUE READING
    65 Citations
    Dysfunctional thalamus-related networks in schizophrenia.
    • D. Pinault
    • Psychology, Medicine
    • Schizophrenia bulletin
    • 2011
    • 90
    • PDF
    Probing thalamic integrity in schizophrenia using concurrent transcranial magnetic stimulation and functional magnetic resonance imaging.
    • 46
    • PDF
    Thalamocortical connectivity during resting state in schizophrenia
    • 92
    Contribution of hippocampal region CA3 to consciousness and schizophrenic hallucinations
    • R. Behrendt
    • Psychology, Medicine
    • Neuroscience & Biobehavioral Reviews
    • 2010
    • 58
    Consciousness, Memory, and Hallucinations
    • 6
    Hallucinatory experience as aberrant event memory formation: Implications for the pathophysiology of schizophrenia
    • R. Behrendt
    • Medicine, Psychology
    • Progress in Neuro-Psychopharmacology and Biological Psychiatry
    • 2016
    • 10

    References

    SHOWING 1-10 OF 194 REFERENCES
    Hallucinations: Synchronisation of thalamocortical γ oscillations underconstrained by sensory input
    • R. Behrendt
    • Medicine, Psychology
    • Consciousness and Cognition
    • 2003
    • 77
    Corticothalamic activation modulates thalamic firing through glutamate "metabotropic" receptors.
    • 450
    • PDF
    A systems model of altered consciousness: integrating natural and drug-induced psychoses
    • 219
    • PDF
    Neuronal activities in brain-stem cholinergic nuclei related to tonic activation processes in thalamocortical systems
    • 724
    • PDF
    Localization of dopamine D4 receptors in GABAergic neurons of the primate brain
    • 472
    Neuronal Nicotinic Receptors in Dementia with Lewy Bodies and Schizophrenia
    • 237
    • Highly Influential