Dysregulation of gastric H,K-ATPase by cigarette smoke extract.

  title={Dysregulation of gastric H,K-ATPase by cigarette smoke extract.},
  author={Muna Hammadi and Mohamed Adi and Rony John and Ghalia A K Khoder and Sherif M. Karam},
  journal={World journal of gastroenterology},
  volume={15 32},
AIM To test whether the expression and activity of H,K-ATPase in parietal cells would be affected by cigarette smoke extract. METHODS Extracts of cigarette smoke were administered into mice by gastric gavage (5 mg/kg body weight/day) for 3 d or in drinking water for 7 or 14 d. For the latter, each day a mouse consumed 5 mL water containing extracts of two cigarettes, on average. Control littermate mice received only vehicle. To compare the amount of H,K-ATPase in control and smoke-treated… CONTINUE READING