Dysregulation of Intracellular Calcium in Alzheimer’s Disease

  title={Dysregulation of Intracellular Calcium in Alzheimer’s Disease},
  author={Marcel Andreas Lauterbach and Volker Westphal and Brian W. Hagen and W. Jonathan Lederer and Stefan W Hell and Raffaele Coppini and Guo Liang Wang and Mei Luo Zhang and Ewout de Vries and Chiara Tesi and Corrado Poggesi and Henk E. D. J. ter Keurs},
14-Symp Dysregulation of Intracellular Calcium in Alzheimer’s Disease Brian J. Bacskai, Kishore V. Kuchibhotla, Carli Lattarulo, Bradley T. Hyman. Massachusetts Gen Hosp, Charlestown, MA, USA. Alzheimer’s disease is characterized by the deposition of senile plaques in the brain resulting in focal neurotoxicity that ultimately leads to neural network disruption. Intracellular calcium is a tightly regulated second messenger whose activation leads to numerous downstream events, including cell… CONTINUE READING
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