Dysregulation of Histone Acetyltransferases and Deacetylases in Cardiovascular Diseases

  title={Dysregulation of Histone Acetyltransferases and Deacetylases in Cardiovascular Diseases},
  author={Yonggang Wang and Xiao Miao and Yucheng Liu and Fengsheng Li and Quan Liu and Jianqin Sun and Lu Cai},
  booktitle={Oxidative medicine and cellular longevity},
Cardiovascular disease (CVD) remains a leading cause of mortality worldwide despite advances in its prevention and management. A comprehensive understanding of factors which contribute to CVD is required in order to develop more effective treatment options. Dysregulation of epigenetic posttranscriptional modifications of histones in chromatin is thought to be associated with the pathology of many disease models, including CVD. Histone acetyltransferases (HATs) and deacetylases (HDACs) are… CONTINUE READING


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