Dysregulation of FGFR Signaling in Human Malignancies

  title={Dysregulation of FGFR Signaling in Human Malignancies},
  author={Mehdi Touat and Ecaterina Ileana and Sophie Postel-Vinay and Fabrice Andr and Jean-Charles Soria},
The fibroblast growth factor signaling pathway (FGFR signaling) is an evolutionary conserved signaling cascade that regulates several basic biologic processes, including tissue development, angiogenesis, and tissue regeneration. Substantial evidence indicates that aberrant FGFR signaling is involved in the pathogenesis of cancer. Recent developments of deep… CONTINUE READING