Dysregulation and functional roles of miR-183-96-182 cluster in cancer cell proliferation, invasion and metastasis

@inproceedings{Ma2016DysregulationAF,
  title={Dysregulation and functional roles of miR-183-96-182 cluster in cancer cell proliferation, invasion and metastasis},
  author={Yi Ma and A-juan Liang and Yu-Ping Fan and Yi-Ran Huang and Xiao-ming Zhao and Yun Wei Sun and Xiang-feng Chen},
  booktitle={Oncotarget},
  year={2016}
}
Previous studies have reported aberrant expression of the miR-183-96-182 cluster in a variety of tumors, which indicates its' diagnostic or prognostic value. However, a key characteristic of the miR-183-96-182 cluster is its varied expression levels, and pleomorphic functional roles in different tumors or under different conditions. In most tumor types, the cluster is highly expressed and promotes tumorigenesis, cancer progression and metastasis; yet tumor suppressive effects have also been… CONTINUE READING

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