Dysregulated module approach identifies disrupted genes and pathways associated with acute myelocytic leukemia.

@article{Fang2015DysregulatedMA,
  title={Dysregulated module approach identifies disrupted genes and pathways associated with acute myelocytic leukemia.},
  author={Yuan Fang and L Xie and X Liu and Z Yu and F-S Kong and N Song and F Zhou},
  journal={European review for medical and pharmacological sciences},
  year={2015},
  volume={19 24},
  pages={4811-26}
}
  • Yuan Fang, L Xie, +4 authors F Zhou
  • Published 2015 in
    European review for medical and pharmacological…
OBJECTIVE To identify disrupted genes and pathways involved in acute myelocytic leukemia (AML) by systematically tracking the dysregulated modules across normal and AML conditions. MATERIALS AND METHODS In this study, we firstly integrated the protein interaction data and expression profiles to infer and reweight the normal and AML networks using Pearson… CONTINUE READING